Novel therapeutic agents for the management of multiple myeloma patients with renal impairment Running head (max 50 characters): Management of MM patients with renal impairment Authors:
نویسندگان
چکیده
Author affiliations: Roswell Park Cancer Institute, Buffalo, NY; Hospital-CIC, Universidad de Salamanca/CSIC, Salamanca, Spain; The Tisch Cancer Institute, Mount Sinai Medical Center, New York, NY; 1st Department of Medicine, Center for Oncology and Haematology, Wilhelminenspital, Vienna, Austria; University of Athens, School of Medicine, Athens, Greece *Current affiliation: Division of Hematology and Oncology, Mayo Clinic Cancer Center, Jacksonville, FL.
منابع مشابه
Novel therapeutic agents for the management of patients with multiple myeloma and renal impairment.
Renal impairment is a major complication of multiple myeloma. Patients presenting with severe renal impairment represent a greater therapeutic challenge and generally have poorer outcome. However, once patients with renal impairment achieve remission, their outcomes are comparable with those of patients without renal impairment. Therapies that offer substantial activity in this setting are need...
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Renal impairment is a common complication of multiple myeloma and deterioration in renal function or renal failure may complicate clinical management. This retrospective study in patients with multiple myeloma using an electronic medical records database was designed to estimate the prevalence of renal impairment (single occurrence of estimated glomerular filtration rate [eGFR] <60 mL/min per 1...
متن کاملCurrent Trends of Renal Impairment in Multiple Myeloma
Background: Renal impairment (RI) is a common complication of multiple myeloma (MM). Around 50% of patients with MM have RI at presentation, and up to 5% require dialysis treatment. Severe acute kidney injury (AKI) as a cause of RI is a particular challenge as historically the survival of patients who sustain this complication and require dialysis is very poor. However, in this current period, ...
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Improved survival among transfusion dependent thalassemia patients in recent years has led to the manifestation of morbidities such as renal dysfunction. Renal injury is still an underestimated complication in β thalassemia major patients. Chronic anemia, iron overload due to repeated transfusion, and specific iron chelators are the main factors in pathogenesis of renal dysfunction in β thalass...
متن کاملCurrent Trends of Renal Impairment in Multiple Myeloma.
BACKGROUND Renal impairment (RI) is a common complication of multiple myeloma (MM). Around 50% of patients with MM have RI at presentation, and up to 5% require dialysis treatment. Severe acute kidney injury (AKI) as a cause of RI is a particular challenge as historically the survival of patients who sustain this complication and require dialysis is very poor. However, in this current period, s...
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